在线日韩日本国产亚洲丨少妇伦子伦情品无吗丨欧美性猛交xxxx免费看蜜桃丨精品人妻系列无码一区二区三区丨亚洲精品无码不卡在线播放

Your Good Partner in Biology Research

Rat Parathyroid hormone,PTH ELISA Kit

  • 中文名稱:
    大鼠甲狀旁腺激素(PTH)酶聯免疫試劑盒
  • 貨號:
    CSB-E07866r
  • 規格:
    96T/48T
  • 價格:
    ¥3900/¥2500
  • 其他:

產品詳情

  • 產品描述:
    大鼠甲狀旁腺激素(PTH)酶聯免疫試劑盒(CSB-E07866r)為雙抗夾心法ELISA試劑盒,定量檢測血清、血漿、組織勻漿樣本中的PTH含量。PTH即甲狀旁腺激素,是甲狀旁腺主細胞分泌的肽類激素。它主要作用于骨和腎臟,調節鈣磷代謝,維持血鈣平衡。研究機制上,其可通過與受體結合激活信號通路,影響骨重建和腎小管對鈣磷的重吸收等。試劑盒檢測范圍為6.25 pg/mL-400 pg/mL,該產品廣泛應用于內分泌機制研究、骨代謝動物模型評價、藥物干預效果驗證等領域,尤其適用于探究甲狀旁腺相關疾病模型中的激素動態變化,或結合其他鈣調節因子進行系統性機制解析。本品僅用于科研,不用于臨床診斷,產品具體參數及操作步驟詳見產品說明書。
  • 別名:
    Pth ELISA Kit; Parathyroid hormone ELISA Kit; PTH ELISA Kit; Parathyrin ELISA Kit
  • 縮寫:
  • Uniprot No.:
  • 種屬:
    Rattus norvegicus (Rat)
  • 樣本類型:
    serum, plasma, tissue homogenates
  • 檢測范圍:
    6.25 pg/mL-400 pg/mL
  • 靈敏度:
    1.56 pg/mL
  • 反應時間:
    1-5h
  • 樣本體積:
    50-100ul
  • 檢測波長:
    450 nm
  • 研究領域:
    Signal Transduction
  • 測定原理:
    quantitative
  • 測定方法:
    Sandwich
  • 精密度:
    Intra-assay Precision (Precision within an assay): CV%<8%
    Three samples of known concentration were tested twenty times on one plate to assess.
    Inter-assay Precision (Precision between assays): CV%<10%
    Three samples of known concentration were tested in twenty assays to assess.
  • 線性度:
    To assess the linearity of the assay, samples were spiked with high concentrations of rat PTH in various matrices and diluted with the Sample Diluent to produce samples with values within the dynamic range of the assay.
     SampleSerum(n=4)
    1:5Average %97
    Range %91-103
    1:10Average %99
    Range %95-107
    1:20Average %95
    Range %90-99
    1:40Average %87
    Range %81-92
  • 回收率:
    The recovery of rat PTH spiked to levels throughout the range of the assay in various matrices was evaluated. Samples were diluted prior to assay as directed in the Sample Preparation section.
    Sample TypeAverage % RecoveryRange
    Serum (n=5) 9389-97
    EDTA plasma (n=4)106102-109
  • 標準曲線:
    These standard curves are provided for demonstration only. A standard curve should be generated for each set of samples assayed.
    pg/mlOD1OD2AverageCorrected
    4002.613 2.511 2.562 2.408
    2002.054 1.953 2.004 1.850
    1001.276 1.287 1.282 1.128
    500.727 0.738 0.733 0.579
    250.457 0.468 0.463 0.309
    12.50.361 0.350 0.356 0.202
    6.250.275 0.269 0.272 0.118
    00.154 0.153 0.154  
  • 數據處理:
  • 貨期:
    3-5 working days

產品評價

相關問答

 常見問題解答
Q:

大鼠PTH ELISA試劑盒是否可拆卸?

A:
是,酶標板是可拆卸的

靶點詳情

  • 功能:
    PTH elevates calcium level by dissolving the salts in bone and preventing their renal excretion. Stimulates [1-14C]-2-deoxy-D-glucose (2DG) transport and glycogen synthesis in osteoblastic cells.
  • 基因功能參考文獻:
    1. PTHrP and PTH mediate wasting through a common mechanism involving PTHR. PMID: 26669699
    2. our data demonstrate that PTH activation of nuclear receptor-associated protein 1 is essential for the effect of PTH to increase FGF23 levels. PMID: 24940803
    3. data support a link between PTH regulating HDAC4 phosphorylation by PKA, trafficking, partial degradation, and the control of MMP-13 transcription through association with Runx2 PMID: 24904057
    4. Mg reduces PTH secretion mainly when a moderate low calcium concentration is present; Mg also modulates parathyroid glands function through upregulation of the key cellular receptors CaR, VDR and FGF23/Klotho system. PMID: 24103811
    5. The persistence of the phosphaturic response to PTH occurs through posttranscriptional mechanisms. PMID: 23344572
    6. The secretory response of parathyroid hormone to acute hypocalcemia in vivo is independent of parathyroid glandular sodium/potassium-ATPase activity. PMID: 21209610
    7. Data suggest that a high concentration of PTH(1-34)-induced cytotoxicity and apoptosis in PC12 cells was associated with upregulation of ERK and p38 through a mitochondria-mediated apoptotic pathway. PMID: 20971569
    8. Study indicates an influence of sex on PTH molecular form secretion or metabolism. PMID: 20627105
    9. Modulation of integrin expression in osteoblastic cells by PTH is likely to be indirect, and phenotypic expression of integrin subtypes is part of the cascade of events that lead to PTH (1-34) mediated osteoblast differentiation. PMID: 11746505
    10. New signaling pathway for parathyroid hormone and cyclic AMP action on extracellular-regulated kinase and cell proliferation in bone cells PMID: 11956184
    11. alterations in PI3K activity in response to parathyroid hormone with aging PMID: 12581861
    12. PTH or PTHrP can exert anabolic effects in the skeleton. PMID: 12631114
    13. that periosteal and endosteal osteoblastic cell populations exhibit metabolic differences in their extracellular matrix responses to PTH PMID: 14514685
    14. the parathyroid hormone-Smad3 axis may have a role in the bone anabolic action of PTH PMID: 14517210
    15. PTH and mechanical stimulation on trabecular bone formation rate suggest a potential benefit for combined PTH administration and exercise in the treatment of osteoporosis. PMID: 14672346
    16. Rho and Rho kinase are an important component of PTH signaling in osteoblastic cells PMID: 15476589
    17. Combinations of radioprotectors may achieve their beneficial additive effects in the growth plate by decreasing the usual early drop in parathyroid hormone-related protein and parathyroid hormone receptor 1 after irradiation PMID: 16494524
    18. Calcium, phosphate & uremia determine parathyroid hormone mRNA stability through binding of protective factors adenosine-uridine rich binding factor 1 & Up-stream of N-ras & recruitment of degradation complex that cleaves parathyroid hormone mRNA[review] PMID: 17565271
    19. FGF23 suppressed both parathyroid hormone (PTH) secretion and PTH gene expression PMID: 17992255
    20. IL-18 is regulated by parathyroid hormone and is required for its bone anabolic actions PMID: 18165223
    21. These data indicate a novel role for KSRP in parathyroid hormone gene expression. PMID: 18583400
    22. Phosphate overload and normal parathyroid hormone infusion induced phenotypic changes in vascular smooth muscle cells, as evidenced by upregulated aortic expression of Runx2. PMID: 19075196
    23. Regulation of PTH mRNA stability by the calcimimetic R568 and the phosphorus binder lanthanum carbonate in chronic kidney disease. PMID: 19129257
    24. without altering the gross chromatin structure, PTH stimulates acetylation of histones H3 and H4 via recruitment of p300 to Runx2 bound to the MMP-13 promoter, resulting in gene activation PMID: 19423655
    25. estrogens regulate PTH indirectly, possibly through FGF23 PMID: 19628670
    26. Parathyroid hormone (PTH) suppresses rat PTH/PTH-related protein receptor gene promoter PMID: 11554727

    顯示更多

    收起更多

  • 亞細胞定位:
    Secreted.
  • 蛋白家族:
    Parathyroid hormone family
  • 組織特異性:
    Hypothalamus and parathyroid gland.
  • 數據庫鏈接:

    KEGG: rno:24694

    STRING: 10116.ENSRNOP00000019199

    UniGene: Rn.9768



主站蜘蛛池模板: 五十路熟女丰满大屁股| 久久俺也去丁香综合色| 日本乱码一区二区三区不卡| 亚洲人成人网站在线观看| 亚洲精品一区二区三区在线| 亚洲三区在线观看内射后入| 亚洲中文字幕无码一去台湾| 久久婷婷五月综合国产尤物app| 国产精品久久久久久久久电影网 | 亚洲欧洲自偷自拍图片| 亚洲综合日韩av无码毛片| 中国产xxxxa片在线观看| 另类 专区 欧美 制服| 精品服丝袜无码视频一区| 一卡二卡3卡四卡网站精品| 日本免费一区二区三区中文字幕| 欧美高清精品一区二区| 国产精品嫩草影院免费观看| 琪琪午夜伦埋影院77| 亚洲熟妇av乱码在线观看| 老司机久久精品最新免费| 综合 欧美 小说 另类 图| 嫩草av久久伊人妇女超级a| 高清无码视频直接看| 日本熟妇人妻xxxxx-欢迎您| 自拍偷自拍亚洲精品牛影院| 人妻无码视频一区二区三区 | 日本在线高清不卡免费播放| 欧美做受视频播放| 精品一二三区久久aaa片| 亚洲乱亚洲乱妇小说网| 浪荡女天天不停挨cao日常视频| 精品免费看国产一区二区| 国产成人精品综合久久久| 亚洲欧洲专线一区| 国产日产欧产精品精品app| 亚洲午夜久久久精品影院| 亚洲日韩中文第一精品| 丁香五月缴情在线| 国产在线视频主播区| 乱熟女高潮一区二区在线|